Schwartz R H, Rodriguez W J, Schwartz D M
Laryngoscope. 1981 Apr;91(4):616-9. doi: 10.1288/00005537-198104000-00016.
Middle ear effusion (MEE) as a residual of treated acute otitis media was found in 49% of 776 children studied. No antibiotic singly or in combination, demonstrated superiority in reducing the incidence of MEE. Simple myringotomy, as a therapeutic modality in 415 children who presented with an acutely bulging painful eardrum, did not facilitate adequate drainage as 51% of such children, treated with simple myringotomy in addition to antibiotics, had MEE detected 10 days later. The incidence of MEE also occurred independently of the middle ear pathogen. Within six weeks, spontaneous resolution of the effusion occurred in 85% of the 382 children with MEE that was detected 10 days after acute otitis media.
在776名接受研究的儿童中,49%被发现存在作为治疗后急性中耳炎残留的中耳积液(MEE)。单独使用或联合使用抗生素,在降低中耳积液发生率方面均未显示出优势。对于415名鼓膜急性膨出且疼痛的儿童,单纯鼓膜切开术作为一种治疗方式,并未促进充分引流,因为在接受单纯鼓膜切开术加抗生素治疗的此类儿童中,51%在10天后被检测出有中耳积液。中耳积液的发生也与中耳病原体无关。在急性中耳炎10天后检测出中耳积液的382名儿童中,85%的患儿在六周内积液自行消退。