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血小板卫星现象：一项超微结构研究。

Platelet satellitism: an ultrastructural study.

作者信息

Payne C M

出版信息

Am J Pathol. 1981 Apr;103(1):116-28.

PMID:7223859
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1903815/
Abstract

The ultrastructural morphology of platelet-polymorph (platelet-polymorphonuclear leukocyte) rosettes was investigated in EDTA-anticoagulated blood obtained from two patients who exhibited the phenomenon of platelet satellitism. Most of the platelet profiles were attached to the polymorph surface by broad areas of contact. Examination of these broad areas of contact at high magnification revealed an intercellular material of low electron density. This material appeared to form strands, which bridged the intercellular space and spanned the entire area formed by the apposing plasma membranes. Phagocytosis of entire platelets was only observed in 1 case. The platelet profiles that participated in rosette formation revealed a large number of glycogen particles, compared with unattached platelets. Ultrastructural examination of "stress" platelets obtained from five normal subjects treated with steroids similarly showed a large number of glycogen particles, although no rosette formation or phagocytosis of platelets was observed. The etiology of platelet satellitism is discussed.

摘要

对两名出现血小板卫星现象的患者的乙二胺四乙酸（EDTA）抗凝血液中血小板 - 多形核白细胞（血小板 - 多形核）玫瑰花结的超微结构形态进行了研究。大多数血小板轮廓通过广泛的接触区域附着在多形核细胞表面。在高倍镜下检查这些广泛的接触区域发现了低电子密度的细胞间物质。这种物质似乎形成了条索，横跨细胞间空间并跨越由相对的质膜形成的整个区域。仅在1例中观察到整个血小板的吞噬作用。与未附着的血小板相比，参与玫瑰花结形成的血小板轮廓显示出大量糖原颗粒。对五名接受类固醇治疗的正常受试者获得的“应激”血小板进行超微结构检查，同样显示出大量糖原颗粒，尽管未观察到血小板玫瑰花结形成或吞噬作用。本文讨论了血小板卫星现象的病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0415/1903815/1c17f0ece163/amjpathol00217-0129-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0415/1903815/aa79122d9624/amjpathol00217-0122-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0415/1903815/54b826efe60d/amjpathol00217-0124-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0415/1903815/cb0cb48d10b9/amjpathol00217-0125-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0415/1903815/af110dc294a7/amjpathol00217-0126-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0415/1903815/d7bdb3e47995/amjpathol00217-0127-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0415/1903815/1c17f0ece163/amjpathol00217-0129-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0415/1903815/aa79122d9624/amjpathol00217-0122-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0415/1903815/54b826efe60d/amjpathol00217-0124-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0415/1903815/cb0cb48d10b9/amjpathol00217-0125-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0415/1903815/af110dc294a7/amjpathol00217-0126-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0415/1903815/d7bdb3e47995/amjpathol00217-0127-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0415/1903815/1c17f0ece163/amjpathol00217-0129-a.jpg

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Platelet satellitism in chronic renal failure: an experimental study.慢性肾衰竭中的血小板卫星现象：一项实验研究。
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Platelet satellitism in infectious disease?传染病中的血小板卫星现象？

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The use of adrenocorticotropic hormone and cortisone in the treatment of leukemia and leukosarcoma.促肾上腺皮质激素和可的松在白血病及淋巴肉瘤治疗中的应用。
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Platelet satellitism: experimental studies.血小板卫星现象：实验研究
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Fine structure of the bond between platelets in artificial thrombi and in platelet aggregates induced by adenosine diphosphate.人工血栓及二磷酸腺苷诱导的血小板聚集体中血小板间连接的精细结构
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