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头颈部纤维瘤病的诊断与治疗(作者译)

[Diagnosis and therapy of fibromatosis in head and neck region (author's transl)].

作者信息

Fritzmeier F, Kronsbein H, Draf W

出版信息

HNO. 1981 Apr;29(4):105-11.

PMID:7228744
Abstract

Fibromatosis is a heterogenous group of soft tissue neoplasias, only some forms of which occur in the head and neck region. In the pathological classification it takes place between the fibroma and fibrosarcoma. With nodular fasciitis, it's subspecies myositis proliferans and aggressive fibromatosis exist differential diagnostic difficulties, especially as it's difficult to exclude fibrosarcoma. The benign myositis proliferans gives an impression of a malignant process by it's rapid proliferation, cell-polymorphia and high mitotic activity. The monomorphous histological picture and the slower proliferation of the aggressive fibromatosis, however can simulate a benign tumor, although thought to be semimalignant. 3-case-reports point out these characteristics. Complete excision is the therapy advised for all fibromatosis. In aggressive fibromatosis a large enough healthy area is the best condition to prevent recidives.

摘要

纤维瘤病是一组异质性的软组织肿瘤,其中只有某些类型发生于头颈部区域。在病理分类中,它介于纤维瘤和纤维肉瘤之间。与结节性筋膜炎相比,其亚型增殖性肌炎和侵袭性纤维瘤病存在鉴别诊断困难,尤其是难以排除纤维肉瘤。良性增殖性肌炎因其快速增殖、细胞多形性和高有丝分裂活性而给人一种恶性过程的印象。然而,侵袭性纤维瘤病的单形性组织学表现和较慢的增殖速度,尽管被认为是半恶性的,但也可能模拟良性肿瘤。3例病例报告指出了这些特征。对于所有纤维瘤病,建议采用完整切除治疗。在侵袭性纤维瘤病中,足够大的健康切缘是预防复发的最佳条件。

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