烟酸对大鼠脑内脑苷脂浓度的影响。

Effect of nicotinic acid on the concentration of cerebroside in rat brain.

作者信息

Nakashima Y, Suzue R

出版信息

J Nutr Sci Vitaminol (Tokyo). 1980;26(4):335-42. doi: 10.3177/jnsv.26.335.

DOI:10.3177/jnsv.26.335

Abstract

The effect of nicotinic acid on the changes of rat brain cerebroside levels has been studied during brain development. There is a gradual increase in the concentration of cerebroside from 12 days of age to adult level at approximately 47 days of age. However, the concentration of cerebroside was significantly lower in brain of rat fed the nicotinic acid-deficient diet. Therefore, nicotinic acid may play an important role in cerebroside synthesis in brain of developing rat.

摘要

在大脑发育过程中，研究了烟酸对大鼠脑内脑苷脂水平变化的影响。从12日龄到约47日龄成年阶段，脑苷脂浓度逐渐升高。然而，喂食烟酸缺乏饮食的大鼠脑内脑苷脂浓度显著较低。因此，烟酸可能在发育中大鼠脑内脑苷脂合成中起重要作用。