Ronco P, Wechsler B, Saillant G, Godeau P
Nouv Presse Med. 1981 May 9;10(21):1707-10.
Four patients with Behçet's disease (a 42-year-old woman and 3 men aged 24, 32 and 39 respectively), who had received high doses of prednisone (0.5 to 1 mg/kg/day) during a mean period of 21 months developed aseptic osteonecrosis of the femoral heads and condyles which obliged to reduce steroid dosage and to introduce additional drugs. Corticosteroids are useful in Behçet's disease, as in other systemic diseases, but they probably act also on the underlying immune vascularitis. The occurrence of pain in weight-bearing joints during treatment should suggest osteonecrosis and in such cases, beside radiography, scintigraphy with technetium and/or phlebography with pressure measurement might provide an early diagnosis.
4例白塞病患者（1名42岁女性和3名男性，年龄分别为24岁、32岁和39岁），在平均21个月的时间里接受了高剂量泼尼松（0.5至1毫克/千克/天）治疗，出现了股骨头和髁的无菌性骨坏死，这迫使减少类固醇剂量并加用其他药物。与其他全身性疾病一样，皮质类固醇在白塞病中是有用的，但它们可能也作用于潜在的免疫性血管炎。治疗期间负重关节出现疼痛应提示骨坏死，在这种情况下，除了X线摄影外，锝骨闪烁显像和/或压力测量静脉造影可能有助于早期诊断。
