Bergen S, Owen J, Snider W R, Lim Y C
Am Surg. 1981 May;47(5):232-5.
A case report of disseminated adenomyomas of the abdominal and pelvic cavities is presented. Although the pathogenesis of these benign tumors is still unresolved, the authors postulate that they develop from the differentiation into smooth muscle of a multi-potential cell that arises from endometrial stromal cells in an area of preexisting endometriosis. Based on the authors' experience, when multiple leiomyomas are found in the peritoneal cavity, it is wise to make serial sections to determine whether endometrial tissue is present. The clinician must be alert to the fact that on gross examination adenomyomas can mimic metastatic carcinoma. Differentiation is made only through histologic examination. In addition, since adenosarcoma arising from adenomyoma is a documented occurrence, careful examination of histologic sections of adenomyomas is essential to avoid making the wrong diagnosis.
本文报告一例腹腔和盆腔播散性腺肌瘤病例。尽管这些良性肿瘤的发病机制仍未明确,但作者推测它们是由预先存在的子宫内膜异位症区域的子宫内膜间质细胞产生的多能细胞分化为平滑肌而形成的。根据作者的经验,当在腹腔中发现多个平滑肌瘤时,明智的做法是制作连续切片以确定是否存在子宫内膜组织。临床医生必须注意,在肉眼检查时,腺肌瘤可能会模仿转移性癌。只有通过组织学检查才能进行鉴别。此外,由于有文献记载腺肌瘤可发生腺肉瘤,因此仔细检查腺肌瘤的组织学切片对于避免误诊至关重要。