Mitterstieler G, Kurz R, Haas H, Desoye G
Padiatr Padol. 1981;16(2):257-65.
45 infants and children with thrombocytopenia and septicemia were studied. Many parameters of blood coagulation, the platelet diameters and the megakaryocytes of the bone marrow (Feulgen stained cytophotometry and maturity of the megakaryocytes) were examined. 15 patients had a consumption coagulopathy and 30 were classified as having an isolated septic thrombocytopenia. In both groups the number of the megakaryocytes of the bone marrow smears were normal. 81% of the megakaryocytes were mature. The patient group with isolated septic thrombocytopenia had significantly greater ploidy values of the megakaryocytes than a control group. In both groups the diameters of the platelets were also significantly greater than in an age matched control group of children with a normal platelet count. These results allow the conclusion that the thrombocytopenia in pediatric patients with septicemia is not caused by a diminished production of platelets.
对45名患有血小板减少症和败血症的婴幼儿进行了研究。检测了许多凝血参数、血小板直径以及骨髓巨核细胞（福尔根染色细胞光度法和巨核细胞成熟度）。15例患者患有消耗性凝血病，30例被归类为单纯性败血症性血小板减少症。两组骨髓涂片巨核细胞数量均正常。81%的巨核细胞成熟。单纯性败血症性血小板减少症患者组巨核细胞的倍性值明显高于对照组。两组患者的血小板直径也明显大于年龄匹配的血小板计数正常儿童对照组。这些结果表明，败血症患儿的血小板减少不是由血小板生成减少引起的。
