清醒和睡眠状态下猫脊髓运动神经元的膜电位和输入电阻

Membrane potential and input resistance of cat spinal motoneurons in wakefulness and sleep.

作者信息

Glenn L L, Dement W C

出版信息

Behav Brain Res. 1981 Mar;2(2):231-6. doi: 10.1016/0166-4328(81)90060-7.

Abstract

An approximation of the membrane resistance - input resistance - was measured with double-barrelled micropipettes in hindlimb motoneurons during wakefulness and the states of sleep in chronically implanted, restrained cats. During postural atonia in rapid-eye-movement (REM) sleep, motoneurons had a sustained hyperpolarization of 5-8 mV and a 30% decrease in input resistance. There was little difference in membrane potential or input resistance between wakefulness and the other sleep states. The results directly support the hypothesis that motoneuron deactivation in REM sleep arises from active inhibition.

摘要

在长期植入并受约束的猫处于清醒和睡眠状态时，使用双管微电极在后肢运动神经元中测量了膜电阻（输入电阻）的近似值。在快速眼动（REM）睡眠中的姿势性肌张力缺失期间，运动神经元持续超极化5 - 8 mV，输入电阻降低30%。清醒状态与其他睡眠状态之间的膜电位或输入电阻几乎没有差异。这些结果直接支持了以下假设，即REM睡眠中运动神经元的失活源于主动抑制。