[Ability of cells in tissue culture to recover from damage caused by chemotherapeutic drugs].

The repair of potential lethal damages was investigated in the LL cell line induced by some chemicals. Three different chemical compounds were used. An inhibitor of DNA synthesis--hydroxyurea, an alkylating agent--methylnitrosourea, and an antibiotic intercalating in DNA--actinomycin D. It was shown that damages induced by hydroxyurea could be repaired. Unlike, the repair of damages induced by methylnitrosourea and actinomycin D was not observed.