Kunze J, Petres J
Fortschr Med. 1981 May 28;99(20):761-4.
New found knowledge concerning the penetration kinetics of anthralin induced us to modify the treatment of psoriasis. The new method was compared in a right-left test with the classical anthralin therapy in 9 patients. After that the entire body was treated with the short-term therapy on 45 patients with severe psoriasis.
once a day 1%-anthralin-5%-salicylic acid vaseline was rubbed over all parts of the skin and after 10 minutes washed off thoroughly. Within a few days the dosage was increased up to 3% anthralin and the application time up to 20 minutes if possible. The treatment was continued on the level according to the individual tolerance. With the new method there was an earlier healing process and the time of treatment was therefore shortened. Moreover after a few days of hospitalization it was possible to continue the treatment at home with cooperative patients, able to go on with their work. Short-time anthralin therapy seems to optimate the classical method.