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辐射后肝脏再生早期核糖核蛋白的形态学

Morphology of nuclear ribonucleoproteins in the early period of liver regeneration after irradiation.

作者信息

Orkisz S, Bartel H

出版信息

Histochemistry. 1981;71(4):629-34. doi: 10.1007/BF00508388.

Abstract

Cytochemical study of hepatocytes nuclei of the liver irradiated with a dose of 650 rad and irradiated after partial hepatectomy was performed. Morphological exponents of the intensive synthesis of preribosomal RNA in the nucleolus, as well as the transcription of heterogeneous RNA contained in perichromatin fibrils were revealed under the ionizing radiation effect. The behavior of perichromatin granules in the course of the experiment suggests delay in the transport of messenger RNA to cytoplasm, influenced by gamma radiation. Nuclear bodies were observed very often in nuclei of hepatocytes of irradiated animals.

摘要

对接受650拉德剂量照射以及部分肝切除后再照射的肝脏肝细胞进行细胞核细胞化学研究。在电离辐射作用下,观察到核仁中前核糖体RNA强烈合成以及染色质周缘纤维中所含异质性RNA转录的形态学指标。实验过程中染色质周缘颗粒的行为表明,信使RNA向细胞质的转运受到γ辐射影响而延迟。在受照射动物的肝细胞细胞核中经常观察到核体。

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