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辐射后肝脏再生早期核糖核蛋白的形态学

Morphology of nuclear ribonucleoproteins in the early period of liver regeneration after irradiation.

作者信息

Orkisz S, Bartel H

出版信息

Histochemistry. 1981;71(4):629-34. doi: 10.1007/BF00508388.

DOI:10.1007/BF00508388
PMID:7263299
Abstract

Cytochemical study of hepatocytes nuclei of the liver irradiated with a dose of 650 rad and irradiated after partial hepatectomy was performed. Morphological exponents of the intensive synthesis of preribosomal RNA in the nucleolus, as well as the transcription of heterogeneous RNA contained in perichromatin fibrils were revealed under the ionizing radiation effect. The behavior of perichromatin granules in the course of the experiment suggests delay in the transport of messenger RNA to cytoplasm, influenced by gamma radiation. Nuclear bodies were observed very often in nuclei of hepatocytes of irradiated animals.

摘要

对接受650拉德剂量照射以及部分肝切除后再照射的肝脏肝细胞进行细胞核细胞化学研究。在电离辐射作用下,观察到核仁中前核糖体RNA强烈合成以及染色质周缘纤维中所含异质性RNA转录的形态学指标。实验过程中染色质周缘颗粒的行为表明,信使RNA向细胞质的转运受到γ辐射影响而延迟。在受照射动物的肝细胞细胞核中经常观察到核体。

相似文献

1
Morphology of nuclear ribonucleoproteins in the early period of liver regeneration after irradiation.辐射后肝脏再生早期核糖核蛋白的形态学
Histochemistry. 1981;71(4):629-34. doi: 10.1007/BF00508388.
2
Morphology of nuclear ribonucleoproteins in the early period of liver regeneration.肝脏再生早期核糖核蛋白的形态学
Histochemistry. 1978 Aug 15;57(1):87-92. doi: 10.1007/BF00507358.
3
Relationship between chromatin and perichromatin granules in cadmium-treated isolated hepatocytes.镉处理的离体肝细胞中染色质与核仁外周颗粒之间的关系。
J Ultrastruct Res. 1981 Mar;74(3):341-50. doi: 10.1016/s0022-5320(81)80125-6.
4
Ultrastructure of hepatocyte nuclei in irradiated, adrenalectomized rats.照射及肾上腺切除大鼠肝细胞细胞核的超微结构
Acta Morphol Hung. 1984;32(3-4):167-73.
5
Perichromatin granules in the liver nuclei after isolation of hnRNP (informofer) particles.分离hnRNP(信息传递因子)颗粒后肝细胞核中的染色质周颗粒
Acta Biol Acad Sci Hung. 1979;30(3):257-64.
6
[Electron microscope examination of chromatin in hepatocyte nuclei within the first hourse after partial hepatectomy, II. The degree of chromatin condensation and the organization of fibrillar RNP components].[部分肝切除术后第一小时内肝细胞核染色质的电子显微镜检查,II. 染色质凝聚程度及纤维状核糖核蛋白成分的组织]
Mol Biol (Mosk). 1979 Nov-Dec;13(6):1312-21.
7
[Incorporation of C14-alanine into the protein of cell nuclei in regenerating liver of irradiated and intact rats].[C14-丙氨酸掺入受辐照和未受辐照大鼠再生肝脏的细胞核蛋白质中]
Biokhimiia. 1967 Nov-Dec;32(6):1145-8.
8
The formation of nucleolar perichromatin granules.核仁外周染色质颗粒的形成。
J Ultrastruct Res. 1981 Aug;76(2):181-91. doi: 10.1016/s0022-5320(81)80016-0.
9
Cytochemical studies on the relation of nucleoside triphosphatase activity to ribonucleoproteins in isolated rat liver nuclei.关于核苷三磷酸酶活性与分离的大鼠肝细胞核中核糖核蛋白关系的细胞化学研究。
J Histochem Cytochem. 1980 Jan;28(1):27-35. doi: 10.1177/28.1.6153190.
10
Increased synthesis of nuclear RNA in regenerating rat liver after gamma-irradiation.γ射线照射后再生大鼠肝脏中核RNA合成增加。
Acta Biochim Biophys Acad Sci Hung. 1975;10(3):147-52.

本文引用的文献

1
SYNTHESIS OF RIBONUCLEIC ACID BY LIVER NUCLEAR AND NUCLEOLAR PREPARATIONS AFTER PARTIAL HEPATECTOMY.部分肝切除术后肝脏细胞核及核仁制剂对核糖核酸的合成
J Biol Chem. 1964 Sep;239:2952-6.
2
NUCLEOPROTEIN CHANGES IN REGENERATING LIVER NUCLEI AFTER X-IRRADIATION.X射线照射后再生肝细胞核中的核蛋白变化
Int J Radiat Biol Relat Stud Phys Chem Med. 1964;8:75-83. doi: 10.1080/09553006414550071.
3
The effect of prior continuous irradiation on the G2, M, and S phases of proliferating parenchymal cells in the regenerating liver.先前连续照射对再生肝实质细胞增殖的G2期、M期和S期的影响。
Radiat Res. 1967 Jun;31(2):304-14.
4
Molecular pathology of irradiation.辐射的分子病理学
Lab Invest. 1966 Jan;15(1 Pt 1):192-5.
5
Hepatocellular ultrastructure during liver regeneration after subtotal hepatectomy.肝大部切除术后肝脏再生过程中的肝细胞超微结构
Exp Mol Pathol. 1966 Oct;5(5):455-74. doi: 10.1016/0014-4800(66)90026-8.
6
Effect of x-irradiation on liver regeneration.X射线辐射对肝脏再生的影响。
Exp Mol Pathol. 1966 Aug;5(4):389-95. doi: 10.1016/0014-4800(66)90041-4.
7
Fine structural organization of the interphase nucleus in some mammalian cells.一些哺乳动物细胞间期细胞核的精细结构组织
J Ultrastruct Res. 1969 May;27(3):266-88. doi: 10.1016/s0022-5320(69)80017-1.
8
RNA polymerase activity in liver nuclei of intact and adrenalectomized gamma-irradiated mice.完整的和肾上腺切除的经γ射线照射的小鼠肝脏细胞核中的RNA聚合酶活性
Experientia. 1970 May 15;26(5):490. doi: 10.1007/BF01898462.
9
The effect of whole-body x-irradiation of guinea pigs on liver ribonucleic acid synthesis.豚鼠全身X线照射对肝脏核糖核酸合成的影响。
Biochem J. 1970 Feb;116(3):503-14. doi: 10.1042/bj1160503.
10
Protein biosynthesis in the liver of X-irradiated mice.X射线照射小鼠肝脏中的蛋白质生物合成
Int J Radiat Biol Relat Stud Phys Chem Med. 1974 May;25(5):445-54. doi: 10.1080/09553007414550621.