一名老年女性中致命的地高辛-奎尼丁相互作用

Fatal digoxin-quinidine interaction in an elderly woman.

作者信息

Pieroni R E, Marshall J

出版信息

J Am Geriatr Soc. 1981 Sep;29(9):422-5. doi: 10.1111/j.1532-5415.1981.tb02382.x.

DOI:10.1111/j.1532-5415.1981.tb02382.x

Abstract

The medical records of an elderly woman revealed strong evidence of a lethal digoxin-quinidine interaction. This case and several problems contributing to digitalis toxicity are presented. Physicians should be more aware of the potential toxicities involved in cardioactive drug therapy in the elderly. Current concepts of the quinidine-digoxin interaction are discussed.

摘要

一位老年女性的病历显示出地高辛与奎尼丁发生致命相互作用的有力证据。本文介绍了该病例以及导致洋地黄中毒的几个问题。医生应更加了解老年人心血管活性药物治疗中潜在的毒性。文中还讨论了奎尼丁与地高辛相互作用的当前概念。