Syreishchikov V V
Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(11):1701-5.
A clinico-epidemiological study was made of 446 patients who suffered from alcoholic psychoses during 1946--1970. An analysis of the quantitative and qualitative modification of the syndromes, the regularities in their dynamics demonstrated that the transformation of the symptomatology to a large extent depend upon the type of development of the alcoholic psychoses. Transitory psychoses are more frequently replaced by psychopathy-like personality changes. In a remittent development, repeated psychoses are characterized, as a rule, by a delirium or hallucinosis. Following a delirium there are typical acute verbal hallucinosis. During relapses there is an increasing amount of atypical symptoms. In patients with mixed and especially a continuous development of the psychoses, the pathokinesis of syndromes proceeds on the level of profound psychopathological disorders. As a result there may be either schizoform and crude organic clinical pictures and eventually there is a deep organic symptomatology (pseudoparalysis), or against the background of crude alcoholic personality changes, after lucid periods, there may be acute psychotic conditions.
对1946年至1970年间患有酒精性精神病的446例患者进行了临床流行病学研究。对综合征的定量和定性改变及其动态规律进行分析后发现,症状学的转变在很大程度上取决于酒精性精神病的发展类型。短暂性精神病更常被类似精神病态的人格改变所取代。在缓解性发展过程中,反复出现的精神病通常以谵妄或幻觉症为特征。谵妄之后会出现典型的急性言语性幻觉症。在复发期间,非典型症状的数量会增加。在患有混合型尤其是持续性精神病发展的患者中,综合征的病理运动在深度精神病理障碍层面上进行。结果可能出现精神分裂症样和严重器质性临床症状,最终出现严重的器质性症状(假性麻痹),或者在严重酒精性人格改变的背景下,在清醒期后可能出现急性精神病状态。