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闭合性颅脑损伤中脑干的病理生理方面(作者译)

[Pathophysiological aspects of the brain stem in closed head injuries (author's transl)].

作者信息

Lausberg G

出版信息

Z Kinderchir. 1981 Jul;33(3):200-6. doi: 10.1055/s-2008-1063120.

Abstract

In a case of severe head injury, there is a disturbance of the functional cycle between hypothalamus/mesencephalon and the cortex cerebri. In this article, the causes and the pathophysiological, functional disturbances of primary and secondary unconsciousness will be discussed. In a case of a posttraumatic intracranial hypertension, the following causes are to be considered: cerebral oedema, intracerebral haematomas and the so-called pneumatocephalus: the collection of air in the ventricle system when open head injuries of the base of the skull occur. The midbrain syndrome which is caused by the compression of the midbrain is characterized by the disturbed reaction of the pupils, convulsive seizures and vegetative dysregulation of respiration, circulation and temperature. When the above-mentioned syndrome persists, it can develop into bulbar syndrome. This is recognized through a severe functional disturbance, which can lead to central brain if the cause of the rise of intracranial pressure is not overcome within one hour.

摘要

在严重颅脑损伤的情况下,下丘脑/中脑与大脑皮层之间的功能循环会受到干扰。本文将讨论原发性和继发性昏迷的病因以及病理生理和功能障碍。在创伤后颅内高压的情况下,应考虑以下病因:脑水肿、脑内血肿以及所谓的气颅:即当颅底开放性颅脑损伤发生时,脑室系统内积气。由中脑受压引起的中脑综合征的特征是瞳孔反应紊乱、惊厥发作以及呼吸、循环和体温的植物神经调节失调。如果上述综合征持续存在,可能会发展为延髓综合征。这通过严重的功能障碍得以识别,如果颅内压升高的原因在一小时内未得到克服,可能会导致中枢性脑损伤。

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