家猫中磷酸己糖异构酶多态性

Phosphohexose isomerase polymorphism in the domestic cat.

作者信息

Auer L, Bell K

出版信息

Anim Blood Groups Biochem Genet. 1981;12(2):89-94. doi: 10.1111/j.1365-2052.1981.tb01537.x.

DOI:10.1111/j.1365-2052.1981.tb01537.x

Abstract

Genetic variation of the enzyme phosphohexose isomerase (PHI) has been found in the erythrocytes of Australian domestic cats by horizontal starch gel electrophoresis at pH 8.2. Three complex patterns of isoenzymes, designated F, FS and S, were obtained migrating anodally. Limited family studies and the distribution of the three main phenotypes indicated that the polymorphism in controlled by two codominant autosomal alleles, PHIF and PHIS. Gene frequencies for PHIF and PHIS have been calculated as 0.036 and 0.964 respectively. Three additional variant forms have also been observed.

摘要

通过在pH 8.2条件下的水平淀粉凝胶电泳，在澳大利亚家猫的红细胞中发现了磷酸己糖异构酶（PHI）的遗传变异。获得了三种复杂的同工酶模式，分别命名为F、FS和S，它们向阳极迁移。有限的家系研究和三种主要表型的分布表明，这种多态性由两个共显性常染色体等位基因PHIF和PHIS控制。已计算出PHIF和PHIS的基因频率分别为0.036和0.964。还观察到另外三种变异形式。