McKenzie J S, Rogers D K
Brain Res Bull. 1981 Oct;7(4):345-52. doi: 10.1016/0361-9230(81)90027-7.
Single units responding to heterotopic somatic stimuli, on extracellular recording in thalamic intralaminar and neighbouring nuclei, also responding to stimulation of the midbrain tegmentum or the medullary magnocellular reticular formation. Consideration of response latencies suggested that some monosynaptic projections from both midbrain and medulla may be received in nuclei centralis lateralis, centrum medianum-parafascicularis complex, and medial ventralis lateralis. Responses to brainstem of nuclei medialis dorsalis, lateralis posterior were of considerably longer latency. There was no correlation between shortness of latency and following-rate of unit responses; the ability of intralaminar neurons to follow rapidly-repeated brainstem stimuli is inferred to be limited by inhibitory processes rather than by synaptic interruptions in the afferent pathway. Conditioning stimuli to caudate nucleus or hippocampus suppressed most intralaminar responses to midbrain stimuli, the shortest-latency responses included, suggesting that inhibitory effects could be exerted at the thalamic level, perhaps directly on the responsive neurone.
在丘脑板内核及相邻核团进行细胞外记录时，对异位躯体刺激有反应的单个神经元，也对中脑被盖或延髓巨细胞网状结构的刺激有反应。对反应潜伏期的研究表明，来自中脑和延髓的一些单突触投射可能在外侧中央核、中央中核-束旁核复合体以及内侧腹外侧核中被接收。背内侧核、后外侧核对脑干的反应潜伏期要长得多。潜伏期的长短与单位反应的跟随率之间没有相关性；板内神经元快速跟随重复脑干刺激的能力被推断为受抑制过程的限制，而非传入通路中的突触中断。对尾状核或海马的条件刺激抑制了大多数板内对中脑刺激的反应，包括最短潜伏期的反应，这表明抑制作用可能在丘脑水平发挥，或许直接作用于反应神经元。
