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铀矿工人的支气管肺泡灌洗术(作者译)

[Broncho-alveolar lavage in uranium miners (author's transl)].

作者信息

Robalo Cordeiro A J, Baganha M F, Carmo J G, Gaspar E, Lima M A, Rosa M A

出版信息

Rev Fr Mal Respir. 1981;9(3):241-56.

PMID:7302347
Abstract

This study on workers in a uranium mine is principally concerned with the characteristics of the cells recovered by LBA. First, alveolar macrophage function was studied (including viability, phagocytic activity, capillary adherence and migratory activity). Secondly the lymphocytes were identified as T, B, and then their mitogenic responses were studied; occurring spontaneously or in response to phytohemagglutinin or purified protein derivative. Finally, the biochemical aspects were examined (including immunoglobulins, total protein, albumin, phospholipids, potassium, calcium, magnesium, complement components, anti-proteases, etc.). We conclude that there were not demonstrable changes in cellular function in either smokers or non smokers in miners subjected to the ambient radiation of a uranium mine.

摘要

这项针对铀矿工人的研究主要关注通过淋巴细胞微核测定法(LBA)回收的细胞的特征。首先,研究了肺泡巨噬细胞功能(包括活力、吞噬活性、毛细血管黏附性和迁移活性)。其次,将淋巴细胞鉴定为T细胞、B细胞,然后研究它们的有丝分裂反应;这些反应可自发发生,或对植物血凝素或纯化蛋白衍生物产生反应。最后,检查了生化方面(包括免疫球蛋白、总蛋白、白蛋白、磷脂、钾、钙、镁、补体成分、抗蛋白酶等)。我们得出结论,在遭受铀矿环境辐射的矿工中,吸烟者和非吸烟者的细胞功能均未出现明显变化。

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