Stanfield J W, Levy J, Kyriakopoulos A A, Waldman P M
Cutis. 1981 Oct;28(4):458-60.
Patients with moderate-to severe dry skin of the lower legs bathed daily for 17 days using either an emulsified lanolin and mineral oil bath additive (Treatment Group) or their usual bath soap (Control Group). The affected sites were evaluated and photographed before and at selected times following treatment, using a standardized technique. The severity of the dry skin as it appeared in projected color transparencies was evaluated on a 10-point grading scale by a second investigator under blinded conditions. The differential response between treatment and control groups increased with time and was found statistically significant (p less than 0.05), demonstrating the sensitivity of the method as well as the apparent therapeutic effects of the bath additive.
患有中度至重度小腿干性皮肤的患者,每天使用乳化羊毛脂和矿物油沐浴添加剂(治疗组)或其常用沐浴皂(对照组)沐浴,持续17天。采用标准化技术在治疗前及治疗后的选定时间对患处进行评估并拍照。由另一位研究者在盲态条件下,根据投射彩色透明片上显示的干性皮肤严重程度,采用10分制评分量表进行评估。治疗组与对照组之间的差异反应随时间增加,且具有统计学意义(p小于0.05),这表明该方法具有敏感性以及沐浴添加剂明显的治疗效果。