[HPLC of trapidil (Rocornal) and metabolites (author's transl)].

Trapidil (1; Rocornal) and 10 metabolites can be separated by a gradient technique on reversed phases (RP-8 instant columns) using the eluents methanol/water and acetonitrile/phosphate buffer (pH = 5.4); ultraviolet detection. Furthermore, HPLC techniques for purity testing and for determining 1 in serum are described.