Darnaud B, Nucci T, Letrone S, Binaghi M, Coscas G
Ann Med Interne (Paris). 1981;132(6):362-6.
Ocular electrophysiology investigations are essential for detecting retinal complications of prolonged treatment with synthetic antimalarial agents. The techniques employed and the principal lesions discovered by the examination are described. The analysis of lesions found in 29 out of 120 cases examined showed that only simple close surveillance was necessary in 17 cases, a reduction in daily dosage in 11 cases, and interruption of treatment in one case only. The modalities of ocular electrophysiology surveillance during prolonged treatment with antimalarial agents are outlined.