Mantravadi R, Katz A M, Skolnik E M, Becker S, Freehling D J, Friedman M
Arch Otolaryngol. 1981 Dec;107(12):735-8. doi: 10.1001/archotol.1981.00790480011003.
Stomal recurrence developed in 5% of the 507 patients who underwent total laryngectomy for a squamous cell carcinoma. The most common site of the primary tumor was the glottis, followed by the supraglottic and pyriform sinus regions. Initial subglottic extension of the tumor and metastatic lymphadenopathy were the most significant risk factors. The primary tumor size, prior emergency tracheostomy, and conservation surgical procedures had no effect on the incidence of stomal recurrence. The median survival in patients with stomal malignant neoplasms was only five months. In high-risk patients, extended dissection or elective postoperative radiotherapy is recommended.
507例因鳞状细胞癌接受全喉切除术的患者中,5%发生了造口复发。原发肿瘤最常见的部位是声门,其次是声门上区和梨状窦区。肿瘤最初的声门下扩展和转移性淋巴结病是最显著的危险因素。原发肿瘤大小、既往急诊气管切开术和保留性手术操作对造口复发率没有影响。造口恶性肿瘤患者的中位生存期仅为5个月。对于高危患者,建议进行扩大清扫或选择性术后放疗。