Gauthier J, Bois R, Allaire D, Drolet M
J Behav Med. 1981 Dec;4(4):407-19. doi: 10.1007/BF00846150.
All combinations of cooling versus warming and finger versus temporal artery were used in the present study, the aim of which was to identify an optimal biofeedback training site and to assess the specific effects of skin temperature biofeedback upon migraine. After an initial 4-week baseline phase, during which daily records of headache activity and medication were kept, 24 migraine patients were randomly assigned to one of the four experimental conditions. Training sessions for all patients were of 50-min duration and occurred once per week for 8 weeks. The headache charts were completed for another 4 weeks after treatment was terminated and again at 6-month follow-up. The results showed significant reductions in migraine activity and drug usage. However, self-regulation of skin temperature in different directions at different sites did not in fact result in significantly different magnitudes of change in migraine activity across groups. The role of nonspecific factors is discussed and a physiological model is proposed to explain how warming and cooling may produce clinical improvement in migraine.
本研究采用了降温与升温以及手指动脉与颞动脉的所有组合方式，目的是确定最佳的生物反馈训练部位，并评估皮肤温度生物反馈对偏头痛的具体影响。在最初为期4周的基线期，在此期间记录每日头痛活动和用药情况，24名偏头痛患者被随机分配到四种实验条件之一。所有患者的训练课程时长为50分钟，每周进行一次，共8周。治疗结束后，头痛图表又持续填写4周，并在6个月随访时再次填写。结果显示偏头痛活动和药物使用显著减少。然而，在不同部位向不同方向进行皮肤温度的自我调节，实际上并未导致各组偏头痛活动的变化幅度有显著差异。文中讨论了非特异性因素的作用，并提出了一个生理模型来解释升温和降温如何在偏头痛中产生临床改善效果。
