Honkanen-Buzalski T, Katila T, Sandholm M
Acta Vet Scand. 1981;22(3-4):360-8. doi: 10.1186/BF03548661.
Milk trypsin-inhibitor levels were followed during clinical and experimental endotoxin-induced mastitis. Milk trypsin-inhibitor level proved to be a good indicator of mastitis, closely relating to milk BSA values. The trypsin-inhibitor pattern in the quarter milk samples during mastitis closely resembled the pattern of BSA, which indicates that the trypsin-inhibitor is blood derived and diffuses to the mammary gland lite albumin. The timing of the increase in the trypsin-inhibitor into the endotoxin infused quarter closely matched with the increase in body temperature, heart rate, decrease in blood leucocytes and increase in somatic cells. Serum zinc and iron showed a decrease a few hours later.
在临床和实验性内毒素诱导的乳腺炎期间，对乳中胰蛋白酶抑制剂水平进行了跟踪。结果证明，乳中胰蛋白酶抑制剂水平是乳腺炎的一个良好指标，与乳中牛血清白蛋白（BSA）值密切相关。乳腺炎期间乳腺四分体乳汁样本中的胰蛋白酶抑制剂模式与BSA模式极为相似，这表明胰蛋白酶抑制剂源自血液，并且像白蛋白一样扩散到乳腺。注入内毒素的乳腺四分体中胰蛋白酶抑制剂增加的时间与体温升高、心率加快、血液白细胞减少以及体细胞增加的时间密切匹配。血清锌和铁在数小时后出现下降。
