Semm P, Demaine C, Vollrath L
Cell Mol Neurobiol. 1981 Sep;1(3):259-69. doi: 10.1007/BF00710681.
Microelectrophoretic application of sex hormones onto pineal cells in guinea pigs has shown different responses in pregnant females as compared to males. In pregnant females estrone caused excitation in 74% of the cells tested, while progesterone and testosterone, prolactin, and HCG were inhibitory in a majority of the cells tested, while progesterone and testosterone, prolactin, and HCG were inhibitory in a majority of the cells. In contrast, in males estrone caused excitation of only 19% but inhibition of 37%. A smaller percentage of cells was inhibited by progesterone, while the predominant response to testosterone was excitation. These results suggest that the pineal gland may be under a feedback control.
对豚鼠松果体细胞进行性激素的微电泳施加实验，结果表明，与雄性相比，怀孕雌性的反应有所不同。在怀孕雌性中，雌酮在74%的受试细胞中引起兴奋，而孕酮、睾酮、催乳素和人绒毛膜促性腺激素在大多数受试细胞中起抑制作用；相比之下，在雄性中，雌酮仅在19%的细胞中引起兴奋，但在37%的细胞中起抑制作用。受孕酮抑制的细胞比例较小，而对睾酮的主要反应是兴奋。这些结果表明，松果体可能受到反馈控制。
