Bernd H J
Klin Monbl Augenheilkd. 1981 Aug;179(2):102-8. doi: 10.1055/s-2008-1057272.
Seventy-eight contact lens patients issued with soft HEMA lenses were examined in order to establish reasons for intolerance. The examination was carried out in conjunction with a questionnaire designed to furnish information about the habits of the contact lens patients. Less than 50% of the patients had been advised to have their lenses checked. Almost all the patients wore their contact lenses all day without interruption. On average they had been wearing the lenses for up to 17 hours per day over a 3.3 year period. In approximately 2/3 of the cases the eye had suffered some damage and in approximately 1/3 of the cases the effects were more serious. Patients who had worn their lenses for even longer periods of time had suffered still more severe eye damage. However, microbiological findings, allergies to the cleaning fluids, reduced tear production, incorrect lens fit and severe deterioration of the lens material were not found to be the prime causes of intolerance. Photographs shot by SEM showed evidence of defects of the corneal surface after the HEMA lens had been worn 18 hours.
对78名佩戴软性甲基丙烯酸羟乙酯(HEMA)镜片的隐形眼镜患者进行了检查,以确定不耐受的原因。检查过程中还结合了一份问卷,旨在提供有关隐形眼镜患者习惯的信息。不到50%的患者曾被建议检查镜片。几乎所有患者都整日不间断地佩戴隐形眼镜。在3.3年的时间里,他们平均每天佩戴镜片长达17小时。约2/3的病例中眼睛受到了某种损伤,约1/3的病例中影响更为严重。佩戴镜片时间更长的患者眼睛损伤更为严重。然而,微生物学检查结果、对清洁液的过敏反应、泪液分泌减少、镜片佩戴不当以及镜片材料严重变质均未被发现是不耐受的主要原因。扫描电子显微镜拍摄的照片显示,佩戴HEMA镜片18小时后角膜表面出现了缺陷迹象。