Giachetti M, Denegri E, Pedroni P, Valtolina M
Quad Sclavo Diagn. 1981 Dec;17(4):495-504.
The following lipidic fractions were determined in a population of patients with acute myocardial infarction (AMI) and in a control group: total cholesterol, triglycerides, total phospholipids, HDL-cholesterol and HDL-phospholipids. The assays were repeated four times during the hospitalization of the patients admitted for AMI. With respect to total cholesterol, triglycerides and HDL-cholesterol, our findings correlated well with the results published in literature, inasmuch as they confirmed positive interrelation for total cholesterol/AMI and triglycerides/AMI ratios and a negative interrelation for HDL-cholesterol/AMI ratio. During the 20 days following infarction, these three parameters decreased to significantly lower values. The relationship linking total phospholipids and HDL-phospholipids to myocardial infarction has not yet been sufficiently investigated and the few available seem rather contradictory. The results which we have obtained seem to indicate a connection between increased total phospholipids and AMI, whereas HDL-phospholipids do not seem to provide any discriminant indication.
在急性心肌梗死(AMI)患者群体和对照组中测定了以下脂质成分:总胆固醇、甘油三酯、总磷脂、高密度脂蛋白胆固醇和高密度脂蛋白磷脂。在因AMI入院的患者住院期间,对这些指标进行了4次重复测定。就总胆固醇、甘油三酯和高密度脂蛋白胆固醇而言,我们的研究结果与文献中发表的结果密切相关,因为它们证实了总胆固醇/AMI和甘油三酯/AMI比值呈正相关,而高密度脂蛋白胆固醇/AMI比值呈负相关。在梗死发生后的20天内,这三个参数降至明显更低的值。总磷脂和高密度脂蛋白磷脂与心肌梗死之间的关系尚未得到充分研究,现有的少数研究结果似乎相互矛盾。我们获得的结果似乎表明总磷脂增加与AMI之间存在联系,而高密度脂蛋白磷脂似乎没有提供任何鉴别性指标。