Normal UV-induced DNA repair synthesis in peripheral leukocytes from patients with malignant melanoma of the skin.

Seventeen patients with malignant melanoma were compared to 24 control subjects regarding UV-induced DNA repair synthesis. Peripheral leukocytes were irradiated with different UV-doses and the DNA-repair synthesis was measured in presence of hydroxyurea. A dose response curve was established for each individual. No statistical differences were observed when melanoma patients were compared to the controls.