无肾山羊的慢性血液透析
Chronic hemodialysis in the anephric goat.
作者信息
Bower J D, Holbert R D, Pearson J E, Jones Q, Bengis R, Berndt W O
出版信息
Nephron. 1980;25(1):34-9. doi: 10.1159/000181750.
The Spanish brush goat (Capra hiricus) was studied as an animal model for the anephric state. This rugged animal has a hardy appetite and offers ready blood access for dialysis and sampling. BUN, plasma creatinine and potassium could be brought to normal values by daily hemodialysis. Continual weight loss, severe anemia and some tendency for the development of hypertension were observed despite dialysis. Maintenance of a healthy rumen proved a continual challenge but was possible by hyperalimentation and vigorous dialysis immediately postnephrectomy.
西班牙刷状山羊（Capra hiricus）被作为无肾状态的动物模型进行研究。这种强壮的动物食欲旺盛，为透析和采样提供了便捷的血液获取途径。通过每日血液透析，血尿素氮、血浆肌酐和钾水平可恢复至正常范围。尽管进行了透析，但仍观察到持续体重减轻、严重贫血以及有发展为高血压的倾向。维持健康的瘤胃始终是一项挑战，但在肾切除术后立即通过高营养疗法和积极的透析是可行的。
Zotero 插件