Otten G, Otten B, Helwing E, Habicht A H, Schubert G E
Zentralbl Allg Pathol. 1978;122(6):528-37.
Folic acid is given intravenously to rats 5 to 10 days after a dichromate induced damage of the kidneys. These injection cause an additional damage in the function and structure of the kidneys, but on the other hand, they induce a cell proliferation detected by the increased uptake of thymidine. This cell proliferation in the kidney-tissue seems to be a part of specific reactions to the folic acid.
在重铬酸盐诱导大鼠肾脏损伤5至10天后,给大鼠静脉注射叶酸。这些注射会对肾脏的功能和结构造成额外损伤,但另一方面,它们会通过胸腺嘧啶核苷摄取增加检测到细胞增殖。肾组织中的这种细胞增殖似乎是对叶酸特异性反应的一部分。