Ehrmann R L, Federschneider J M, Knapp R C
Am J Obstet Gynecol. 1980 Mar 15;136(6):737-46. doi: 10.1016/0002-9378(80)90450-0.
In order to properly stage patients with ovarian carcinoma, we are routinely removing and microscopically examining sample aortic lymph nodes in these patients, since aortic lymph node metastases may affect long-term survival. Inasmuch as benign glandular inclusions can be found in pelvic and aortic lymph nodes, we have run into difficulty distinguishing such inclusions from genuine metastases in cases of low-grade or borderline serous ovarian carcinomas. Atypical epithelium in these tumors may closely resemble the lining of benign glandular lymph node inclusions. Moreover, like metastases benign glandular inclusions may grow in the peripheral sinusoid, show epithelial papillae and psammoma bodies, and may even proliferate as small sheets of cells. Just how crucial it is to recognize aortic lymph node metastases in these low-grade tumors will be clarified when the prognostic importance of aortic node metastases becomes understood.
为了准确地对卵巢癌患者进行分期，我们常规切除并显微镜检查这些患者的主动脉旁淋巴结样本，因为主动脉旁淋巴结转移可能影响长期生存。由于在盆腔和主动脉旁淋巴结中可发现良性腺性包涵体，我们在区分低级别或交界性浆液性卵巢癌病例中的此类包涵体与真正转移灶时遇到了困难。这些肿瘤中的非典型上皮可能与良性腺性淋巴结包涵体的内衬极为相似。此外，与转移灶一样，良性腺性包涵体可能生长于外周血窦，呈现上皮乳头和砂粒体，甚至可能呈小片状细胞增殖。当主动脉旁淋巴结转移的预后重要性得到认识时，就会清楚在这些低级别肿瘤中识别主动脉旁淋巴结转移有多关键。
