在铅中毒患者青霉胺治疗全过程中，尿δ-氨基乙酰丙酸作为一种生物学指标。
Urinary delta-aminolevulinic acid as a biological indicator throughout penicillamine therapy in lead intoxication.
作者信息
Molina-Ballesteros G, Zuñiga-Charles M A, Sanchez-Anzaldo F J, Gonzalez-Ramirez J D
出版信息
Arch Environ Health. 1978 Nov-Dec;33(6):308-13. doi: 10.1080/00039896.1978.10667353.
A group of 121 patients with occupational lead exposure was studied. Saturnism was confirmed in 42 of them. Patients were given D-penicillamine in doses of 0.75 and 1.5 g/day. Urinary delta-aminolevulinic acid was selected as a toxicity biological indicator; its concentrations were quantified daily during therapy. Urinary delta-aminolevulinic acid is considered a good biological indicator throughout penicillamine therapy and also in the detection of lead intoxication. Likewise, the chelating test is considered an excellent method to confirm the diagnosis of lead poisoning.
对一组121名职业性铅暴露患者进行了研究。其中42人被确诊为铅中毒。给予患者每日剂量为0.75克和1.5克的D-青霉胺。选择尿δ-氨基乙酰丙酸作为毒性生物学指标；在治疗期间每天对其浓度进行定量。尿δ-氨基乙酰丙酸在整个青霉胺治疗过程中以及铅中毒检测中都被认为是一个良好的生物学指标。同样，螯合试验被认为是确诊铅中毒的极佳方法。
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