Serum and urinary amino acid pattern in schistosomal infection among Egyptians.

The amino acid pattern in plasma and urine of Bilharzial Egyptian patients with different degrees of complications was investigated. The results obtained showed that in mansoniasis, accumulation of amino acids in the circulation is due to derangement in liver function which retards the utilization of amino acids in protein synthesis particularly in the advanced stage of the disease. This is also in part due to liver cell degeneration which parallel the severity of the infection. Aminoaciduria in haematobiasis is partly an overflow type, while in severe cases urinary tract tissue degeneration may be a participating factor. Aminoaciduria in haematobiasis is due to haematuria and urinary tract tissue degeneration.