Dorus E
Arch Gen Psychiatry. 1980 May;37(5):587-94. doi: 10.1001/archpsyc.1980.01780180101013.
Two kinds of variability in the Y chromosome have been assessed in relation to variability of human behavior. The first is the presence of a supernumerary Y chromosome, which is found in two karyotypic variants, 47,XYY and 48,XXYY. The second is inherited variability in the length of the Y chromosome, which results from variability in the length of the quinacrine-binding fluorescent segment. In this article, I review the evidence that these two kinds of variability in the Y chromosome are related to variability of human behavior, and I indicate the methodological and statistical difficulties that are encountered in assessments of such a relationship. My final purpose is to underscore the need for mapping of the Y chromosome and to elucidate the function of the constitutive heterochromatin that constitutes its fluorescent segment so that progress can be made in the study of the Y chromosome and the possible effect of its variability on behavior.
关于人类行为的变异性，人们已对Y染色体的两种变异性进行了评估。第一种是额外的Y染色体的存在，在两种核型变体中可以发现，即47,XYY和48,XXYY。第二种是Y染色体长度的遗传性变异，这是由喹吖因结合荧光片段长度的变异导致的。在本文中，我回顾了Y染色体的这两种变异性与人类行为变异性相关的证据，并指出了在评估这种关系时所遇到的方法学和统计学上的困难。我的最终目的是强调对Y染色体进行图谱绘制的必要性，并阐明构成其荧光片段的组成型异染色质的功能，以便在Y染色体及其变异性对行为可能产生的影响的研究中取得进展。
