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[Interaction of the genes of progressive muscular dystrophy (PMD) and blood groups (ABO)].

作者信息

Milani-Comparetti M, Valentini B, Capriotti M, Dellantonio R, Donati D, Lucchetti L, Nataloni P

出版信息

Boll Soc Ital Biol Sper. 1980 Mar 30;56(6):542-4.

PMID:7378187
Abstract

Verification of the hypothesis that the inheritance of the Progressive Muscular Dystrophies (PMD) may involve dispersed genes, throiugh the study of a sample of 105 patients revealed that 82% of the Duchenne type belong to blood group O, while 79% of the limb-girdle type belong to group A. The fact that the Duchenne gene is sex-linked while the ABO locus is on chromosome 9 confirms the "dispersed genes" hypothesis, with important implications for further research, for genetic counselin and possibly for prevention.

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