大鼠虹膜中的神经生长因子。
Nerve growth factors in the rat iris.
作者信息
Ebendal T, Olson L, Seiger A, Hedlund K O
出版信息
Nature. 1980 Jul 3;286(5768):25-8. doi: 10.1038/286025a0.
DOI:10.1038/286025a0
PMID:7393320
Abstract
Nerve growth factor (NGF) activity was not detected by bioassay in irides killed immediately after excision but NGF appeared within 24 h in living irides placed in culture or grafted to a host eye. Furthermore, sensory and, although less effective, sympathetic denervation of irides in situ led within 10 days to the appearance of NGF activity. In addition, freezing and thawing released a parasympathetic neuronotrophic factor activity from irides.
摘要
在切除后立即处死的虹膜中，通过生物测定法未检测到神经生长因子（NGF）活性，但在置于培养物中或移植到宿主眼中的活虹膜中，24小时内出现了NGF。此外，对虹膜进行原位感觉去神经支配（虽然效果较差，但交感神经去神经支配）在10天内导致NGF活性出现。另外，冻融从虹膜中释放出一种副交感神经神经营养因子活性。
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