Konegawa R
Nihon Heikatsukin Gakkai Zasshi. 1978 Jun;14(1-2):29-41. doi: 10.1540/jsmr1965.14.29.
The role of the antral gastric vagi and the pyloric sphincter on the residual stomach following proximal gastrectomy were studied electromyographically, using adult mongrel dogs. At the first stage of surgery, proximal gastrectomy was performed preserving the bilateral antral gastric vagi followed by esophagogastrostomy by end-to-side anastomosis. The residual stomach was equipped with four bipolar silver needle electrodes and two waterproof strain gauges on the wall of the stomach. At the second and third stage of surgery, the same dog subsequently underwent trancal vagotomy and pyloromyotomy at 4 weeks intervals. Following proximal vagotomy, the interval of the BER in fasting was prolonged. Dysrhythmia was observed quite frequently, and the amplitude and rhythmicity of contractile activities of the residual stomach became lowered and distorted, however, after feeding the interval of the EBR was shortened and dysrhythmia was altered to a regular rhythmic pattern. Frequent episodes of vomiting were observed following over feeding. Subsequent trancal vagotomy showed increased incidence of dysrhythmia in fasting, and gave no favourable effects on the vomiting episodes or the amount of feeding. After pyloromyotomy, the amount of feeding could be increased by about 50% from the original optimal amount.
利用成年杂种犬，通过肌电图研究了胃窦部迷走神经和幽门括约肌在近端胃切除术后残胃中的作用。在手术的第一阶段，进行近端胃切除术，保留双侧胃窦部迷走神经，然后行端侧吻合的食管胃吻合术。在残胃壁上安装四个双极银针电极和两个防水应变片。在手术的第二和第三阶段，同一只犬随后每隔4周依次进行经腹迷走神经切断术和幽门肌切开术。近端迷走神经切断术后，空腹时BER的间隔延长。心律失常相当频繁地出现，残胃收缩活动的幅度和节律性降低且紊乱，然而，喂食后EBR的间隔缩短，心律失常转变为规则的节律模式。喂食过多后观察到频繁呕吐。随后的经腹迷走神经切断术显示空腹时心律失常的发生率增加，对呕吐发作或喂食量没有产生有利影响。幽门肌切开术后，喂食量可从原来的最佳量增加约50%。
