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儿童一氧化碳中毒

Carbon monoxide intoxication in children.

作者信息

Binder J W, Roberts R J

出版信息

Clin Toxicol. 1980 May;16(3):287-95. doi: 10.3109/15563658008989951.

Abstract

Carbon monoxide poisoning is currently a danger of ill-defined proportions in the pediatric population. A patient with possible residual neurologic effects from carbon monoxide as well as a retrospective study of pediatric patients with acute diagnosis of carbon monoxide poisoning has been presented. Although it has been impossible to conclude from these cases alone that carbon monoxide can produce residual neurological injury in children, evidence to support this concern can be found in the data presented and existing literature. First, the acute manifestations of carbon monoxide poisoning in the children are similar to those reported for adults who are known to suffer from residual neurological effects. Second, experimental studies in neonatal animals have produced effects which persist several weeks to months after the acute exposure to carbon monoxide. More information is needed regarding the long-term effects of carbon monoxide on the pediatric population. It may be totally inappropriate to establish "safe carbon monoxide levels" for children on the basis of experience from adult exposure.

摘要

目前,一氧化碳中毒在儿科人群中是一种比例不明的危险情况。本文介绍了一名可能因一氧化碳中毒而有残留神经效应的患者,以及一项对急性诊断为一氧化碳中毒的儿科患者的回顾性研究。尽管仅从这些病例中无法得出一氧化碳会对儿童产生残留神经损伤的结论,但在所呈现的数据和现有文献中可以找到支持这一担忧的证据。首先,儿童一氧化碳中毒的急性表现与已知会出现残留神经效应的成人所报告的表现相似。其次,对新生动物的实验研究表明,在急性接触一氧化碳后,其影响会持续数周甚至数月。关于一氧化碳对儿科人群的长期影响,还需要更多信息。基于成人接触情况的经验为儿童确定“安全一氧化碳水平”可能是完全不合适的。

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