Godement P, Saillour P, Imbert M
J Comp Neurol. 1980 Apr 15;190(4):611-26. doi: 10.1002/cne.901900402.
The projections, and more particularly the ipsilateral projections, from the retina to the dorsal lateral geniculate nucleus (dlGn) and the superior colliculus have been investigated in adult mice of the C57BL/6J strain after rearing in one of four different conditions: 1) after normal visual experience; 2) after unilateral enucleation at birth; 3) in mice with congenital unilateral anophthalmia (in which only one eye develops) 4) in mice with congenital unilateral microphthalmia (in which one eye is of reduced size while the other is normal). In neonatally enucleated and congenitally monocular mice there is an aberrant uncrossed pathway to regions of the dlGn and the superior colliculus which do not normally receive such a projection. This projection is limited in its distribution; in both the neonatally enucleated and the congenitally monocular animals the uncrossed projection does not reach the lateral and dorsal parts of the dlGn and it only innervates the rostral half of the superior colliculus. The density of the uncrossed pathway in these animals is highest in those regions in which the normal uncrossed pathway terminates. In microphthalmic mice the expansion of the uncrossed pathway is less marked than in monocular mice. In the superior colliculus the aberrant uncrossed projections innervate the stratum griseum superficiale where they are often found distributed in small patches. An intertectal crossing of retinal fibers is described from the contralateral superior colliculus to the deprived ipsilateral superior colliculus.
在C57BL/6J品系的成年小鼠中，于四种不同条件下饲养后，研究了从视网膜到背外侧膝状核（dlGn）和上丘的投射，尤其是同侧投射：1）正常视觉经验后；2）出生时单侧眼球摘除后；3）先天性单侧无眼小鼠（仅一只眼睛发育）；4）先天性单侧小眼小鼠（一只眼睛尺寸减小而另一只正常）。在新生期摘除眼球和先天性单眼小鼠中，存在一条异常的不交叉通路至dlGn和上丘中通常不接受此类投射的区域。该投射分布有限；在新生期摘除眼球和先天性单眼动物中，不交叉投射均未到达dlGn的外侧和背侧部分，且仅支配上丘的 Rostral 半部分。这些动物中不交叉通路的密度在正常不交叉通路终止的区域最高。在小眼小鼠中，不交叉通路的扩展不如单眼小鼠明显。在上丘中，异常的不交叉投射支配浅灰质层，在那里它们常呈小斑块状分布。描述了视网膜纤维从对侧上丘到同侧被剥夺上丘的顶盖间交叉。
