Tarlov E
Surg Clin North Am. 1980 Jun;60(3):565-91. doi: 10.1016/s0039-6109(16)42136-5.
Clinical suspicion is essential for early diagnosis of acoustic neuroma. No absolutely characteristic pattern of hearing loss occurs, and atypical presentations are the rule. The diagnosis of acoustic neuroma is possible by tests that can be performed on an outpatient basis. A hearing loss for high tones with impaired speech discrimination is frequently seen. Testing of the acoustic reflexes and particularly the brain stem auditory-evoked responses (BAER) are becoming the most reliable methods of defining hearing loss in patients suspected of having an acoustic neuroma. High-resolution, thin-sectioning, overlapping-cut CT scanning including CT pneumography when necessary and polytomography of the internal auditory meatus are the mainstays of radiologic evaluation. Complete removal of the tumor at one operation is usually possible by the suboccipital retromastoid route with preservation or restoration of normal brain stem function and preservation of facial nerve function. Preservation of hearing has occasionally been accomplished, and the potential occasionally exists for restoration of hearing in patients with favorable smaller tumors, which have not acquired extensive arterial supply in common with the cochlea. The two factors that most influence results are early diagnosis and gentleness of surgical manipulation of the tissues that is made possible by magnification and illumination with the operating microscope.
临床怀疑对于听神经瘤的早期诊断至关重要。听力损失不存在绝对典型的模式,非典型表现很常见。通过门诊可进行的检查能够诊断听神经瘤。常可见到高音调听力损失且言语辨别能力受损。声反射测试,尤其是脑干听觉诱发电位(BAER)测试,正成为确定疑似听神经瘤患者听力损失最可靠的方法。高分辨率、薄层、重叠扫描的CT扫描,必要时包括CT气脑造影以及内耳道体层摄影,是放射学评估的主要手段。通常可通过枕下乳突后入路一次性完整切除肿瘤,同时保留或恢复正常脑干功能以及面神经功能。偶尔能实现听力保留,对于较小且情况良好、未与耳蜗共同获得广泛动脉供血的肿瘤患者,偶尔也存在恢复听力的可能。最影响结果的两个因素是早期诊断以及借助手术显微镜的放大和照明对组织进行轻柔的手术操作。