Dymond D S, Jarritt P H, Britton K E, Langley D, Spurrell R A
Postgrad Med J. 1978 Oct;54(636):641-8. doi: 10.1136/pgmj.54.636.641.
A study was undertaken to evaluate the role of positive infarct scintigraphy in the diagnosis of acute myocardial infarction (AMI), using Technetium99m stannous pyrophosphate (Tc-PYP) and a portable gamma camera. Sixty-one patients admitted to the Coronary Care Unit (CCU) with a presumptive diagnosis of AMI or ischaemic cardiac pain were studied. Positive scans were present in 24/25 (96%) patients with AMI and new Q waves, and in 10/12 (83%) patients with AMI and no Q waves. Nine of eleven (82%) patients with chest pain and no infarction had negative scans. Of thirteen patients with unstable angina, ten (77%) had positive scans. A further eight patients undergoing coronary artery bypass surgery for angina pectoris were studied pre- and postoperatively. Two patients had strongly positive postoperative scans. The Tc-PYP scan is valuable in the detection of peri-operative infarction following coronary artery surgery, and in patients with unstable angina the technique may detect small amounts of myocardial necrosis undetectable by more conventional means. When the diagnosis of infarction is obvious from the ECG, enzymes, or a combination of the two, the Tc-PYP scan provides no extra information helpful in patient management.
采用锝99m焦磷酸亚锡(Tc-PYP)和便携式γ相机进行了一项研究,以评估阳性梗死闪烁显像在急性心肌梗死(AMI)诊断中的作用。对61例入住冠心病监护病房(CCU)、初步诊断为AMI或缺血性心前区疼痛的患者进行了研究。在24/25例(96%)有AMI且出现新Q波的患者以及10/12例(83%)有AMI但无Q波的患者中,扫描结果为阳性。11例胸痛且无梗死的患者中有9例(82%)扫描结果为阴性。13例不稳定型心绞痛患者中,10例(77%)扫描结果为阳性。另外对8例因心绞痛接受冠状动脉搭桥手术的患者在术前和术后进行了研究。2例患者术后扫描结果呈强阳性。Tc-PYP扫描在检测冠状动脉手术后的围手术期梗死方面很有价值,对于不稳定型心绞痛患者,该技术可能检测到用更传统方法无法检测到的少量心肌坏死。当根据心电图、酶或两者结合能明显诊断梗死时,Tc-PYP扫描并不能提供有助于患者管理的额外信息。