Suzuki T, Ishii Y, Yonekura Y, Hamanaka D, Torizuka K, Mukai T, Fujita T
Radioisotopes. 1978 Oct;27(10):584-9. doi: 10.3769/radioisotopes.27.10_584.
As 81mKr is a radioactive noble gas which has a very short half-life of 13 seconds, it leads no environmental contamination in a laboratory room. Because of its low radiation dose in the human body, it had many merits in routine tests of the inhalation and perfusion scintigraphy, which were very useful extremely in infants, old men and severe patients in need of cooperation. The studies with 81mKr were, either, useful as a load test, since these could repeatedly readily, evaluate the ventilation and perfusion dynamics before and after administration of drugs and show the distribution of the ventilation and perfusion correspond to the various lung volume level.
由于81mKr是一种放射性惰性气体,其半衰期非常短,仅为13秒,因此在实验室环境中不会造成环境污染。因其在人体中的辐射剂量较低,在吸入和灌注闪烁显像的常规检查中具有诸多优点,这对婴儿、老年人以及需要配合的重症患者极为有用。使用81mKr进行的研究也可作为负荷试验,因为这些研究能够轻松地反复评估给药前后的通气和灌注动态,并显示通气和灌注的分布与不同肺容积水平相对应。