Keagy B A, Pharr W F, Thomas D D, Bowes D E
Arch Surg. 1980 Oct;115(10):1199-202. doi: 10.1001/archsurg.1980.01380100045010.
A review of 291 carotid arteries that were subjected to both oculoplethysmography/carotid phonoangiography (OPG/CPA) and arteriography showed that although 84% of the vessels that were narrowed less than 40% were properly categorized by the noninvasive test, there was poor grading ability for lesions 40% or greater, and an unacceptably high (40%) false-negative rate for marked carotid stenoses. This has been confirmed by others. Analysis of a 15-item questionnaire that was returned by 12 clinicians showed an unwarranted reliance on the OPG/CPA as a screening test in those patients without transient ischemic attacks. A large majority of responding physicians favored endarterectomy in asymptomatic patients with lesions greater than 70%, and the use of OPG/CPA prevented a substantial number of affected individuals from undergoing angiography and subsequent corrective surgery.
对291条同时接受眼体积描记法/颈动脉血管音造影(OPG/CPA)和动脉造影的颈动脉进行的回顾显示,尽管无创检测能正确分类84%狭窄小于40%的血管,但对于40%或更高程度的病变,分级能力较差,对于明显的颈动脉狭窄,假阴性率高得难以接受(40%)。其他人也证实了这一点。对12位临床医生返回的一份包含15项内容的问卷分析显示,在没有短暂性脑缺血发作的患者中,对OPG/CPA作为筛查测试存在不必要的依赖。绝大多数做出回应的医生倾向于对病变大于70%的无症状患者进行内膜切除术,OPG/CPA的使用使大量受影响个体免于接受血管造影和随后的矫正手术。