Maylin G A, Rubin D S, Lein D H
Cornell Vet. 1980 Jul;70(3):272-89.
A survey of selenium and vitamin E concentrations in horses was conducted at four breeding farms in New York. There were no significant changes in mean blood selenium concentrations in horses at the three sampling dates whereas vitamin E concentrations underwent seasonal fluctuations. The mean blood selenium concentration in this survey for horses fed local feed was 7.7 microgram/dl. Horses fed commercial feed had a mean blood selenium concentration of 15.6 microgram/dl. A 0.94 correlation coefficient was found between blood glutatione peroxidase activity and blood selenium concentrations in horses. The effect of oral and parenteral selenium administration on blood selenium concentrations and blood glutathione peroxidase activity was also investigated. Oral supplementation of 1 mg selenium per day increased blood selenium concentrations above levels associated with myodegeneration in horses and foals. Parenteral supplementation trials with mares at late gestation indicate that only limited amounts of selenium cross the placental barrier. Parenteral supplementation of mares during gestation and lactation or supplementation of foals beginning at birth will increase blood selenium levels in foals above that associated with selenium/vitamin E deficiency.
在纽约的四个繁殖农场对马匹的硒和维生素E浓度进行了一项调查。在三个采样日期，马匹的平均血硒浓度没有显著变化，而维生素E浓度出现了季节性波动。在本次调查中，喂食当地饲料的马匹平均血硒浓度为7.7微克/分升。喂食商业饲料的马匹平均血硒浓度为15.6微克/分升。马匹血液中谷胱甘肽过氧化物酶活性与血硒浓度之间的相关系数为0.94。还研究了口服和注射硒对血硒浓度和血液谷胱甘肽过氧化物酶活性的影响。每天口服1毫克硒可使马匹和幼驹的血硒浓度升高至高于与肌变性相关的水平。对妊娠后期母马进行的注射补充试验表明，只有有限量的硒能穿过胎盘屏障。在妊娠和哺乳期对母马进行注射补充或从出生开始对幼驹进行补充，将使幼驹的血硒水平高于与硒/维生素E缺乏相关的水平。
