Hirsch M, Verge D, Bouchaud C, Escaig J
Tissue Cell. 1980;12(3):437-47. doi: 10.1016/0040-8166(80)90034-8.
The spatial arrangement of tight junctions in choroid plexus and ciliary body rabbit epithelia has been determined by studying freeze-fracture complementary replicas. In the choroid plexus epithelium, the interruptions of the junctional P-face fibrils were measured to be 14% in their total length. In the ciliary body epithelium, where the fibrils were found to be more fragmented than in the choroid plexus, the P-face fibril interruption accounted for 12% of the total length of the zonulae occludentes sealing the non-pigmented cells and 30% in the focal linear tight junctions connecting the non-pigmented cells at their apices. In both epithelia, the interruptions of the ridges are precisely complemented by particles or short bars of similar length found in the E-face furrows. Consequently, it is possible to conclude that the junctional fibrils are continuous in these two epithelia. For the zonulae occludentes, this continuity appears to be inconsistent with the 'leaky' properties of these epithelia shown by some physiological investigations.
通过研究冷冻断裂互补复制品，已确定兔脉络丛和睫状体上皮中紧密连接的空间排列。在脉络丛上皮中，连接面P面纤维的中断长度占其总长度的14%。在睫状体上皮中，发现纤维比脉络丛中的更破碎，封闭非色素细胞的紧密连接带的P面纤维中断占总长度的12%，而在连接非色素细胞顶端的局灶性线性紧密连接中占30%。在这两种上皮中，嵴的中断都与E面沟中发现的长度相似的颗粒或短棒精确互补。因此，可以得出结论，这两种上皮中的连接纤维是连续的。对于紧密连接带而言，这种连续性似乎与一些生理学研究所显示的这些上皮的“渗漏”特性不一致。
