Caldarelli M, Di Rocco C, Iannelli A
Epilepsia. 1980 Dec;21(6):587-96. doi: 10.1111/j.1528-1157.1980.tb04312.x.
The effects of induced increases in intracranial pressure (ICP) on epileptic activity following topical application of penicillin on the cerebral cortex or dorsal hippocampus were investigated in rabbits. Enhanced basal epileptic activity was brought about by the rise in the ICP, obtained with repeated lumbar infusions of saline. In some animals, this increased activity was already evident during the test, while in others it became obvious only at the end of the procedure. When induced, the increased epileptic activity could persist even after the ICP had returned to within normal limits.
在兔子身上研究了通过反复腰椎注射生理盐水诱导颅内压（ICP）升高对在大脑皮层或背侧海马局部应用青霉素后癫痫活动的影响。通过反复腰椎注射生理盐水使颅内压升高，从而增强了基础癫痫活动。在一些动物中，这种增加的活动在测试期间就已经很明显，而在另一些动物中，只有在手术结束时才变得明显。当诱发癫痫活动增加时，即使颅内压已恢复到正常范围内，这种增加的活动仍可能持续。
