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[乌克兰苏维埃社会主义共和国麻疹流行病学与预防的当前问题。计划免疫期间出现麻疹不利疫情形势的原因]

[Current problems in the epidemiology and prevention of measles in the Ukrainian SSR. Reasons for the unfavorable epidemic situation with respect to measles which developed during the years of planned immunization].

作者信息

Merenkova A M, Tsipershteĭn M Ia

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1980 Aug(8):100-5.

PMID:7445862
Abstract

In the first years of specific mass immunization (1969--1971) the epidemic situation in the Ukrainian SSR was more favorable than during the following period (1976--1977). With time after immunization the protection of the vaccinees decreased. The main reason of the measles virus circulation, of regular epidemics and the aggravation of the epidemic situation in 1976 and 1977 was the presence of 10% of seronegative children, which amounts to more than a million children unprotected against measles in the republic, and the decrease of the immune stratum of the children who had led measles (who played a definite role in the suppression of the epidemic process in 1969--1971) from 40% to 12%. The primary task of measles control is to improve the quality of the vaccine and the system of vaccination. The epidemiological parameters characteristic of measles at present and the results of the serological study of immunity suggest the absence of epidemiological indication for mass revaccination at the present moment.

摘要

在特定大规模免疫接种的头几年(1969 - 1971年),乌克兰苏维埃社会主义共和国的疫情形势比随后时期(1976 - 1977年)更为有利。随着免疫接种时间的推移,疫苗接种者的保护作用下降。1976年和1977年麻疹病毒传播、定期流行以及疫情形势加剧的主要原因是存在10%的血清阴性儿童,这在该共和国相当于超过100万儿童未受到麻疹保护,并且患过麻疹(在1969 - 1971年疫情过程抑制中发挥了一定作用)的儿童免疫阶层从40%降至12%。控制麻疹的首要任务是提高疫苗质量和疫苗接种体系。目前麻疹的流行病学参数以及免疫血清学研究结果表明,目前不存在大规模再次接种的流行病学指征。

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