Acker D, Frigoletto F D, Birnholz J C, Umansky I, Phillippe M, Finberg H J, Lieberman M
Am J Obstet Gynecol. 1980 Dec 15;138(8):1200-4. doi: 10.1016/s0002-9378(16)32792-2.
Ultrasound-facilitated intrauterine transfusion was performed on 35 fetuses. Eleven fetuses were hydropic and less than 26 weeks' gestation at the time of the first intrauterine transfusion (IUT). Only two (18%) neonates survived. Twelve fetuses were not hydropic and less than 26 weeks' gestation at time of IUT. Six (50%) neonates survived. Corrected neonatal survival rates for three hydropic and nine nonhydropic fetuses transfused after 26 weeks were 100% and 78%, respectively. The presence of ascites documented by ultrasound is an adequate indication for an IUT and permitted earlier detection of sicker fetuses; however, as a therapeutic aid, ultrasound neither diminished the fetal morbidity and mortality associated with the procedure nor completely eliminated the need for radiography to confirm proper intra-abdominal localization of the transfusion tubing.
对35例胎儿实施了超声引导下宫内输血。11例胎儿为水肿胎儿，首次宫内输血（IUT）时孕周小于26周。仅2例（18%）新生儿存活。12例胎儿非水肿胎儿，IUT时孕周小于26周。6例（50%）新生儿存活。26周后接受输血的3例水肿胎儿和9例非水肿胎儿的校正新生儿存活率分别为100%和78%。超声检查发现的腹水是进行IUT的充分指征，且能较早发现病情较重的胎儿；然而，作为一种治疗辅助手段，超声既未降低与该操作相关的胎儿发病率和死亡率，也未完全消除通过放射检查来确认输血管道在腹腔内正确定位的必要性。
