利多卡因毒性

Lidocaine toxicity.

作者信息

Brown D L, Skiendzielewski J J

出版信息

Ann Emerg Med. 1980 Dec;9(12):627-9. doi: 10.1016/s0196-0644(80)80475-6.

Abstract

Lidocaine is recognized as a first line drug for ventricular arrhythmias and has recently been used in acute myocardial infarction as prophylaxis against ventricular fibrillation. A 68-year-old man was erroneously given 2 gm of lidocaine by intravenous push and sustained a cardiac arrest. He was treated supportively and had complete recovery. We discuss complications of therapeutic and excessive doses of lidocaine and outline measures for treatment of massive lidocaine overdose.

摘要

利多卡因被公认为治疗室性心律失常的一线药物，最近已用于急性心肌梗死以预防心室颤动。一名68岁男性被错误地静脉推注了2克利多卡因，随后发生心脏骤停。他接受了支持性治疗并完全康复。我们讨论了治疗剂量和过量利多卡因的并发症，并概述了大量利多卡因过量的治疗措施。