Wolfe J D, Trevor E D, Kjeldsberg C R
Cancer. 1980 Dec 15;46(12):2648-53. doi: 10.1002/1097-0142(19801215)46:12<2648::aid-cncr2820461219>3.0.co;2-1.
Three patients with mycosis fungoides who developed pulmonary abnormalities are described. These abnormalities are correlated with the findings at open lung biopsy and at autopsy. The roentgenographic changes consisted of bilateral, nodular pulmonary infiltrates in two patients, and interstitial infiltrate and plate-like atelectasis with hilar adenopathy in a third patient. Examination of lung biopsies and autopsy tissue revealed interstitial and/or intra-alveolar infiltrates composed of atypical lymphoid cells similar to those seem in the skin biopsies. The short survival after detection of an abnormal chest film suggests that dissemination of mycosis fungoides to the lung heralds a poor prognosis.
本文描述了3例蕈样肉芽肿患者出现肺部异常的情况。这些异常与开胸肺活检及尸检结果相关。X线表现为：2例患者出现双侧结节状肺部浸润，第3例患者出现间质浸润、盘状肺不张伴肺门淋巴结肿大。肺活检及尸检组织检查显示，间质和/或肺泡浸润由非典型淋巴细胞组成，与皮肤活检所见相似。胸部X线片出现异常后生存期短，提示蕈样肉芽肿扩散至肺部预示预后不良。
