Sung R T, Hsieh K H, Wang T R
Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 1980 Jun;13(2):201-8.
A 4-year old boy with chronic eczema since early infancy had been admitted thrice to the hospital because of recurrent staphylococcal infections including furunculosis, lymphadenitis, pneumonia and pyothorax. Exhaustive immunologic studies revealed normal humoral, cell-mediated and non-specific immunities except extremely high serum IgE level and dysfunctions of granulocytes including decreased Fc and complement receptors, lowered chemotactic response (around the lower range of normal), slightly impaired intracellular killing of staphylococci and possibly impaired reactions to candida and BCG. In spite of long-term antimicrobial prophylaxis, cold abscesses continued to appear and the eczematous skin lesions waxed and waned.
一名自婴儿早期就患有慢性湿疹的4岁男孩因反复出现葡萄球菌感染，包括疖病、淋巴结炎、肺炎和脓胸，已三次入院。详尽的免疫学研究显示，除血清IgE水平极高以及粒细胞功能障碍（包括Fc和补体受体减少、趋化反应降低（接近正常范围下限）、对葡萄球菌的细胞内杀伤略有受损以及对念珠菌和卡介苗的反应可能受损）外，体液免疫、细胞介导免疫和非特异性免疫均正常。尽管进行了长期抗菌预防，冷脓肿仍不断出现，湿疹性皮肤病变反复消长。
